KEGG   REACTION: R00706
Entry
R00706                      Reaction                               
Name
3-oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating)
Definition
3-Oxopropanoate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H+
Equation
C00222 + C00010 + C00006 <=> C00024 + C00011 + C00005 + C00080
Comment
NAD+ (see R00705)
Reaction class
RC00001  C00005_C00006
RC00004  C00010_C00024
RC02723  C00024_C00222
Enzyme
1.2.1.18
Pathway
rn00410  beta-Alanine metabolism
rn00562  Inositol phosphate metabolism
rn00640  Propanoate metabolism
rn01100  Metabolic pathways
rn01200  Carbon metabolism
Module
M00013  Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18
     R00706  3-Oxopropanoate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H+
Orthology
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Other DBs
RHEA: 22991

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (3)   
Gene (7344)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (7343)   
All databases (7367)   

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